[The clinical significance of the stromal reaction of the head and neck cancer].

of cells were investigated using a micrometer. Concerning blood vessels examinations of the endothelium and the basal membrane of the vessels stained by ABC method using anti-factor VIII antibody were reformed. As for clinical factors, recurrence stage, existence of the local or distant metastasis, clinical prognosis, and non-specific immunoparameters including lymphocytes, T cell and B cell populations, etc. were studied. The clinical significance of the interstitial reaction was examined statistically based on the above results.